Scientific Editorial & Integrity Review

The reviewers identified on this page provide independent scientific accuracy review of the Company's published claims and citations. They do not provide medical advice, render diagnoses, prescribe treatments, or otherwise provide medical services to readers or customers. Their review is editorial in nature and is limited to assessing whether the Company's published claims accurately reflect the underlying scientific literature.

OTA formulations are purpose-built for transparency, meaningful results, and better living. Our mission to develop evidence-based natural formulations grounded in both traditional wisdom and modern clinical science.

To ensure accuracy and transparency, our product pages, clinical studies, and ingredient science are reviewed by independent medical professionals with verifiable credentials and research backgrounds.

We apply a multiple-review standard utilizing medical professionals including MD, PhD, and RN practitioners to help ensure a wide range of review.

Current Independent Scientific Reviewers

Mark Matus, MD

Medical Doctor, Neuroscience & Neurovascular Research
Review Completed: October 2025

Credentials & Background

Doctor of Medicine (MD), University of Debrecen, 2013–2020

Research Fellow, Neuroanesthesia & Neuroscience – Mayo Clinic (2020–2022)

PhD Researcher, Cerebrovascular Imaging & Neurovascular Physiology – Semmelweis University (2022–Present)

Founder & Medical Director – Matus Medical

Healthcare & Regulatory Consultant

Review Scope: Logic Lion’s Mane formulation, clinical claims, and supporting human trial data.

Expert Review Statement:

“I reviewed Logic Lion’s Mane and its referenced clinical study (La Monica et al., Nutrients 2023). The study, a randomized double-blind, placebo-controlled crossover in 40 healthy adults, showed acute cognitive improvements (attention, working memory, reaction time) at 60–120 minutes following 1 g of standardized Lion’s Mane extract. Logic provides 970 mg/day of the same standardized ingredient in liquid form; this minor difference and the study’s sponsor funding are transparently disclosed.”
— Mark Matus, MD

External Profile:
https://www.matusmedical.com/about

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Ryan Hakim, MD

Neurocognitive Disorders Post-Doctoral Research Fellow
Review Completed: November 20, 2025

Credentials & Background

Doctor of Medicine (MD), Loyola University Chicago – Stritch School of Medicine (2020–2024)

Post-Doctoral Neurocognitive Research Fellow, University of Texas Health Science Center at Houston (2025–Present)

Incoming Neurology Resident Physician, University of Arizona

Neuro-Imaging Clinical Research Scholar, Epilepsy Monitoring Unit – UC San Diego Health (2024–2025)

Research focus: neuroimaging, addiction neuroscience, quantitative MRI/PET imaging, and clinical pharmacology

Review Scope: Logic Lion’s Mane formulation, clinical claims, and supporting human trial data.

Expert Review Statement:

“After reviewing Logic Lion’s Mane and its referenced randomized, double-blind, placebo-controlled crossover trial (La Monica et al., Nutrients 2023), I found that the product’s core claims—acute support for attention, working memory, and reaction time in healthy adults—are consistent with the study’s findings following a ~1 g dose of standardized Lion’s Mane extract assessed 60–120 minutes after ingestion. The study’s methodology provides novel and well-controlled observations of short-term cognitive enhancement, while also aligning with the broader scientific literature suggesting that Lion’s Mane may support aspects of cognitive function. Notably, the crossover design—where each participant serves as their own control—adds methodological rigor and strengthens confidence in the reliability of the acute effects reported. Logic’s liquid formulation provides a comparable daily amount (970 mg) of the same clinically studied ingredient and presents these nootropic benefits without making disease-treatment claims, while clearly disclosing study sponsorship and formulation differences. Overall, the website’s scientific positioning is evidence-aligned and transparent, with the important caveat that current data support short-term cognitive effects in healthy adults rather than long-term outcomes or use in clinical populations.”
— Ryan Hakim, MD

External Profile:
https://www.upwork.com/freelancers/~01b4eb93840b3f152a

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Carolina A. Figueroa, MS Nutrition, PhD

Credentials & Background
MS in Nutrition; PhD (nutrition/metabolism) — independent researcher/consultant in clinical-nutrition science.
Review Completed: November 2025

Credentials & Background

“Logic Lion’s Mane and its supporting randomized clinical trial (La Monica et al., Nutrients, 2023) provide evidence that a single 1 g dose of Nordic Lion’s Mane improved working memory, attention, and reaction time after 2 hours, and enhanced subjective happiness and life satisfaction starting at 1 hour compared with placebo. These effects were consistent and observed without adverse events, suggesting that Logic Lion’s Mane may support acute cognitive and mood enhancement in healthy adults.”
- Carolina A. Figueroa, MS Nutrition, PhD

External Profile: https://www.linkedin.com/in/carolinaafigueroa/

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Miranda Adams, RN, BSN, CGRN

Registered Nurse
Review Completed: September 29, 2025

Credentials & Background

Registered Nurse, Mayo Clinic

Bachelor of Science in Nursing

Certified Gastroenterology Registered Nurse (CGRN)

Clinical experience in hospital-based internal medicine and interdisciplinary care

Review Scope: Website clinical information accuracy, ingredient descriptions, health-related language, and safety framing.

Expert Review Statement:

“The advertised product Logic Lion’s Mane by the brand Of The Ancients has been determined to be clinically accurate. Overall, the correlation between the product’s claims and the study’s findings is strong. The clinical evidence supports the advertised benefits, particularly the acute cognitive improvements observed at the two-hour mark. However, further peer review and additional research could reinforce the generalizability of these results to wider populations.”
— Miranda Adams, RN, BSN, CGRN

External Profile:

https://www.linkedin.com/in/miranda-adams-rn-bsn-cgrn-b265b4387

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Editorial Independence Statement

Medical reviewers assess scientific accuracy only. They do not endorse products, nor are they compensated for sales. Their role is to verify that:

Clinical statements align with evidence

Disclosures and disclaimers are properly presented

This ensures consumer transparency and evidence-based communication.

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Review Timeline

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Next Review Scheduled:

Q3 2026 — or earlier if new clinical evidence emerges.

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Questions About Our Clinical Review Process?

Contact our Science & Quality team:
hello@oftheancients.com